Evaluation of Different Extracts of Stem of Verbesina encelioides (Cav.) Benth and Hook ex f. A. Gray for their Anti-inflammatory and Antimicrobial Activity

By : Sharmila , Ram Avatar Sharma , Richa Bhardwaj

Page No: 334-342

Abstract:
Medicinal plants possess several active components like alkaloids, triterpenoids, essential oils and phenolic compounds etc which are responsible for their curative properties. Verbesina encelioides (Cav.) Benth and Hook ex f. A. Gray (family Asteraceae) is an invasive species found in arid or semi-arid regions. It is an herbaceous, annual, tall plant bearing yellow flowers. In the present study, stem of V. encelioides was extracted in water, methanol and pet ether. Those extracts were evaluated for their in vitro anti-inflammatory and antibacterial potential. Results indicated that methanolic extracts showed the maximum activity among all extracts. Methanolic extracts were further subjected for GCMS analysis to determine phytochemical composition. Undecane, p-Cresol, Dodecane, 1-Butanol, 3-methyl-, acetate, Tetradecane, Octadecane, 5-methyl-, Pentadecane, 3-methyl-, Diethyl Phthalate, Glutinol, Eicosane, Heptadecane, 3-methyl-, 6-Hydroxy-4,4,7a-trimethyl-5,6,7,7a-tetrahydr 2.06 Octadecane, n-Hexadecanoic acid, Heptadecanoic acid, 15-methyl-, methyl ester, Lanosta-7,9(11)- etc. compounds have been identified. These findings underscore the importance of further investigation into the specific mechanisms of action and the therapeutic applications of V. encelioides extracts in managing inflammatory and infectious diseases.

Authors:
Sharmila: Research Scholar, Department of Botany, University of Rajasthan, Jaipur, Rajasthan,
Ram Avatar Sharma: Head, Department of Botany, University of Rajasthan, Jaipur, Rajasthan,
Richa Bhardwaj: Assistant Professor, Department of Botany, IIS University, Jaipur, Rajasthan,
 

DOI: https://doi.org/10.32381/JPSR.2025.41.02.14