Biological Efficacies and Biochemical Characterization of Bioactive Compounds from Green Algae, Halimeda opuntia (Linnaeus) J.V. Lamouroux

By : Venkatesh Sakthivel , Sankaralingam Subbiah , Kathiresan Durairaj , Muthuvel Uthayasuriyan , Muthumani Mahalingam

Page No: 254-269

Abstract:
In the present study the sulfated polysaccharides were extracted from Halimeda opuntia and partially purified by using a Diethylaminoethyl cellulose (DEAE-C) column. These sulfated polysaccharides were subjected further to evaluate their biological efficacies. The antibacterial activity of polysaccharides showed a maximum inhibition zone against Salmonella typhi. Free radical scavenging activity of Halimeda opuntia sulfated polysaccharides was assessed by total antioxidant capacity, reducing power assay, hydrogen peroxide scavenging activity, DPPH and ABTS assay. All these assays exhibited that the antioxidant activity of sulfated polysaccharides was concentration oriented. The sulfated polysaccharides also showed rich sources of antidiabetic efficacy. Sulfated polysaccharides have been increasingly studied over the years in the pharmaceutical field, given their potential usefulness in applications such as the design of drug delivery systems. The biochemical characterization of sulfated polysaccharides was studied and confirmed by the Fourier Transform Infrared Spectroscopy (FTIR), High Performance Liquid Chromatography (HPLC) and Gas Chromatography–Mass Spectrometry (GC-MS) analysis.
 

Authors:
Venkatesh Sakthivel::Research Scholar, PG and Research Department of Botany, Saraswathi Narayanan College, Madurai Kamaraj University, Madurai, Tamil Nadu,
Sankaralingam Subbiah: Associate Professor, PG and Research Department of Botany, Saraswathi Narayanan College, Madurai Kamaraj University, Madurai, Tamil Nadu, India.
Kathiresan Durairaj: Associate Professor, PG and Research Department of Botany, Saraswathi Narayanan College, Madurai Kamaraj University, Madurai, Tamil Nadu,
Muthuvel Uthayasuriyan: Research Scholar, PG and Research Department of Botany, Saraswathi Narayanan College, Madurai Kamaraj University, Madurai, Tamil Nadu, 
Muthumani Mahalingam:Research Scholar, PG and Research Department of Botany, Saraswathi Narayanan College, Madurai Kamaraj University, Madurai, Tamil Nadu,
 

DOI: https://doi.org/10.32381/JPSR.2025.41.02.6