Screening of Antibacterial Activity and Phytochemical Analysis of Acalypha Indica L.: A Study with Clinical Aspect

By : M. Guru Sekhar , K.R. Shanmugam , K. Siva Prasad , Ch. Ramakrishna

Page No: 377-381

Abstract
Acalypha indica L. is a medicinal plant which is found in India, Bangladesh, Srilanka and other Asian countries. Acalypha indica L. is used traditionally for treating diabetes, asthama, bacterial and viral diseases. The objective of this current investigation was to study the qualitative, quantitative estimation and anti-bacterial activity of ethanolic and methanolic extracts of Acalypha indica L. This medicinal plant has secondary metabolites like alkaloids, phenols, saponins, steroids, flavonoids and cardiac glycosides.Total tannins, flavonoids and phenol content on a dry weight basis ranged from 0.21-0.36 mg TAE/g, 0.02-1.47 mg QE/g, 0.53-0.82 mg GAE/g respectively. Ethanolic and methanolic extract of Acalypha indica L. showed good antibacterial activity against bacterial strains. Thus our study reported that Acalypha indica L. possess antibacterial effect due to the presence of phytochemicals, so it can be used to treat bacterial diseases.

Authors:
M. Guru Sekhar : Department of Zoology, Government Degree College, Cumbum, Andhra Pradesh, India.
K.R. Shanmugam : Department of Zoology, PRR & VS Government Degree College, Vidavalur, Andhra Pradesh, India.
K. Siva Prasad : Department of Zoology, Government Degree College, Gudur, Andhra Pradesh, India.
Ch. Ramakrishna : Department of Marine Bio-Food Sciences, College of Fisheries and Ocean Sciences, Chonnam National University, Yeosu, Korea
 

DOI: https://doi.org/10.32381/JPSR.2024.40.03.3