Evaluation of Cytotoxic Activities of Methanolic Extracts of Calotropis procera (Aiton) W.T. Aiton

By : Prantik Hazra, Arghya Ghosh

Page No: 190-196

Abstract
The present study aimed to investigate, the Brine shrimp activities and the larvicidal activities of Methanolic leaves and flower extracts of Calotropis procera. The larvicidal activities were studied on Anopheles, Culex, and Chironomus. Surviving larvae and brine shrimps were counted after every 3 hours up to 24 hours and the percentage of death at each dose and control was determined. The LC50 value of Brine Shrimps was 125 mg/ml at 24 hrs, for Anopheles larvae the value of this sample was 50 μg/ml at 24 hrs, for Culex larvae,75 μg/ml at 21 hrs, and for Chironomus larvae, 125 μg/ml at 18 hrs. Death of larvae was increased with the increased concentration of crude extract. However, the outcome of the study failed to show acute toxic effects on brine shrimp and Chironomus larvae; but significant toxicity was observed in methanolic leaf extracts of Calotropis procera in mosquito larvae. This could have serious implications in vector control strategies and minimizing impact on the environment.

Authors:
Prantik Hazra : Assistant Professor, Department of Zoology, Darjeeling Government College, Darjeeling, West Bengal, India.
Arghya Ghosh : Assistant Professor, Department of Botany, Jhargram Raj College, Jhargram, West Bengal, India.
 

DOI: https://doi.org/10.32381/JPSR.2024.40.01.20