Phytochemical Properties of Paederia cruddasiana Prain: A Medicinal Vine Used in Healing of Bone Fractures in Folk Medicine of Assam

By : Pronab Mudoi, B. K. Konwar

Page No: 85-94

Abstract
Kolialota (Paederia cruddasiana Prain), a vine belonging of the family Rubiaceae often used by traditional healers in Assam, India for treating bone fractures with sound results. However, there is no systematic research on the phytochemicals as well as on anabolic actions in bone healing. The study was taken up to analyze the phytochemicals and their biochemical activities present in the leaves of Kolialota. Results clearly refer to the terpenoids and flavonoids, which were found to be abundantly present in the leaves giving significant antioxidant properties. Among the tested extracts, methanolic extract was found to contain higher amounts of total phenols, flavonoids and antioxidants. In addition, the leaf extract was found to contain the high amount of calcium (3993 µg/L ) conformed by scanning electron microscope and energy dispersive analysis. Further, gas chromatography and mass spectroscopic studies also confirmed the presence of certain phytochemicals such as lidocaine and 4 dehydroxy-n-tyramine that are associated with bone anabolic properties.

Authors :
Pronab Mudoi and B. K. Konwar : Department of Molecular Biology and Biotechnology, Tezpur University, Tezpur, Assam, India.
 

DOI: https://doi.org/10.32381/JPSR.2023.39.03.9