An Approach to Understand the Concept of Additional Peaks while Bioanalysis through LC-MS/MS

By : Anjana Rizal, Bratati Roy, C P Malik

Page No: 225-239

Abstract
Additional peaks refers to all unwanted peaks appear in the chromatogram beside the peak of interest. These peaks are extraneous which can be visualized with the aid of detector .In mass spectrometry the analysis is based on m/z ration of the analyte which interms very specific and accurate hence additional peaks always challenge the authenticity of the analysis. Therefore the cause and rectification of additional or unwanted peaks should be investigated as per regulatory requirements while bioanalysis. This research article comprises the facts and figures with the support of in-house experiments and result to understand and eradicate the extra peaks during bioanalysis of drugs.

Authors :
Bratati Roy, Anjana Rizal, and C.P. Malik : Jaipur National University, Jaipur, India