Isolation and Identification of Bioactive Compounds from Argemone mexicana Flower Extract by 1H-NMR and FTIR

By : Aziz Mohammad Khan, Seema Bhadauria, Rajesh Yadav

Page No: 165-170

Abstract
The plant Argemone mexicana is used for medicinal purposes including antimicrobial, larvicidal, nematicidal and wound healing. The present study is aimed to isolate and identify some of the bioactive compounds from Argemone mexicana flower di-ethyl ether extract which are responsible for antimicrobial activity. The pure compound was isolated from the methanol extract of Argemone mexicana using chromatographic methods, including column chromatography and thin layer chromatography. The isolated compound was further characterized by 1H-nuclear magnetic resonance spectroscopy (1H-NMR) and FTIR analysis. The FTIR spectrum showed the presence of major functional groups. From the results of NMR data, the compound is found to be oleic acid (C18H34O2 ) which has important role in antibacterial and antifungal activity

Authors :
Aziz Mohammad Khan : Department of Microbiology, JECRC University, Jaipur - 303905, India
Seema Bhadauria : Department of Botany, University of Rajasthan, Jaipur- 302004, India
Rajesh Yadav : Department of Zoology, JECRC University, Jaipur - 303905, India
 

DOI: https://doi.org/10.32381/JPSR.2019.35.02.3