Evaluation of antibacterial properties of (Z)-7-methoxy-1, 5-dihydrobenzo[c] oxepine isolated from Curcuma caesia Roxb.

By : Arghya Ghosh

Page No: 131-134

Abstract :
The assessment of antimicrobial potentiality of (Z)-7-methoxy-1, 5-dihydrobenzo[c] oxepine was the primary objective of this study. Assessment of its antimicrobial activity was performed using disc diffusion assay respectively. The bioactive compound was terpenoid in nature. The MIC values tested against different pathogenic bacteria. The MIC values of this mono-terpenoid was 150 ?g/ml for the bacterium Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Streptococcus pyogenes, Streptococcus agalactiae, Klebsiella pneumonia, Citrobacter freundii, Proteus vulgaris and 200 ?g/ml for the bacterium Acinetobacter baumannii, Enterococcus faecalis, Proteus mirabilis, Vibrio cholerae respectively. This is the first report of the bioactive nature of (Z)-7-methoxy- 1, 5- dihydrobenzo[c]oxepine against above microorganisms. Due to its antimicrobial property it may function in ethnomedicinal purpose.

Author :
Arghya Ghosh : Assistant Professor, under graduate and post graduate department of Botany, Darjeeling Govt College, Darjeeling, West Bengal, India.

DOI: https://doi.org/10.32381/JPSR.2020.36.1-2.17