Herbal Antimicrobials also Induce the Resistant Bacterial Strain Development - APreliminary Study in Comparison with Commercial Antibiotics

By : M.Michael Babu , S. Kavitha , T.Citarasu , S.Albin Dhas , T.Selvaraj

Page No: 31-49

Abstract
This work was designed to study the effect of commercial antibiotics and herbal antimicrobials on development of resistant strain in the aquatic bacterial pathogens such as Vibrio harvi, Aeromonas hydrophila, Vibrio parahaemolyticus, Vibrio damselae and Vibrio angularium. The aquatic bacterial pathogens were treated with commercial antibiotics and partially purified herbal antimicrobials obtained from Adathoda zeylanica, Cynodon dactylon, Solanum trilobatum, Solanum surratense and Ocimum sanctum. The resistant strain developments in bacteria due to the treatment of antibiotic and herbal antimicrobials were studied by treating the pathogenic bacteria with Less than Threshold Concentration (LTC) of the antibiotics and herbal anti microbial for four subsequent treatments with uniform intervals. From this work, it was evidenced that apart from antibiotics, the herbal antimicrobials also induced resistant strain development in bacteria. The duration and concentration of treatment with commercial antibiotics and herbal antimicrobials were found effective for the development of resistant strain in bacteria. The commercial antibiotics and herbal antimicrobials when mixed and applied on bacteria, reduced the percentage of resistant strain development than applied them separately.

Authors :
Michael Babu M, Kavitha. P, Citarasu. T, Albin Dhas. S and Selvaraj T
Centre for Marine Science and Technology, Manonmaniam Sundaranar University, Rajakkamangalam – 629 502, Kanyakumari District, Tamil Nadu, India.